| CBD Supermarket Knowledge Centre .
A new study has found that cannabidiol oil may bring relief to those who suffer from Crohn’s disease. Crohn’s is one of many types of inflammatory bowel disease that plague those who have it with debilitating symptoms like diarrhoea, stomach cramps, bloody stools, fatigue, and weight loss.
There is currently no cure for Crohn’s. Patients must rely on treatments that target the symptoms, such as steroidal medications or invasive surgery to remove parts of the digestive tract. CBD oil may provide a less intrusive treatment option for Crohn’s patients.
In a placebo-controlled study lead by researchers in Israel, over 65% of patients who participated saw their condition go into clinical remission after 8 weeks of treatment with cannabidiol oil. Only 35% of the placebo group met the strict criteria for clinical remission.
Cannabidiol, or CBD, is known to have anti-inflammatory properties that can help relieve the symptoms of many medical conditions. Medical professionals previously believed this is how CBD abated the symptoms of many irritable bowel diseases, but the recent study showed that this might not be the case.
“We have previously demonstrated that cannabis can produce measurable improvements in Crohn’s disease symptoms but, to our surprise, we saw no statistically significant improvements in endoscopic scores or in the inflammatory markers we measured in the cannabis oil group compared with the placebo group,” said Dr Timna Naftali, the lead researcher.
“We know that cannabinoids can have profound anti-inflammatory effects but this study indicates that the improvement in symptoms may not be related to these anti-inflammatory properties.”
Dr Naftali instead believes that the reduction in symptoms may be related to CBD’s interactions with the endocannabinoid system. Cannabinoids and naturally occurring cannabinoid-like chemicals bind to receptors in the endocannabinoid system, helping the body maintain a healthy balance by regulating mood, sleep, stress, appetite, and pain response.
The endocannabinoid system also has a profound impact on the digestive tract. One of the main cannabinoid receptors, CB-2, is found primarily in the immune system and digestive system. While further research is needed to determine exactly how CBD relieves Crohn’s disease symptoms, it’s possible that CBD binds to CB-2 receptors to help improve energy storage and nutrient transport, which are both impacted by Crohn’s.